The purpose of these two 90 minute webinars (May 11, 2-3:30 PM ET and June 29, 2015, 2-3:30 PM ET) is to illustrate key issues and challenges related to the implementation of Project Lazarus as a model prescription drug overdose prevention program by highlighting major lessons learned (i.e., 'what went well', 'what did not go well' and 'what needed to change') in both the hub activities (the components of the Project Lazarus model that reflect a community-based, bottom-up public health approach) and in the spoke activities (the components that reflect a medical and law enforcement-based, top-down public health approach). Discussions following didactic presentations on lessons learned by key Project Lazarus stakeholders will elicit discussions based on personal experiences, concerns and solutions from webinar participants. Materials presented during the webinar, as well as summaries of discussions, will be condensed into a white paper by the UNC Injury Prevention Research Center and made available for the general public.